Visualization of Adult Stem Cells Within Their Niches Using the Drosophila Germline as a Model System
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The germaria of the fruit fly Drosophila melanogaster present an excellent model to study germline stem cell–niche interactions. Two to three adult stem cells are surrounded by a number of somatic cells that form the niche. Here we describe how Drosophilae germaria can be dissected and specifically immuno-stained to allow for identification and analysis of both the adult stem cells and their somatic niche cells.
