• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Protocols for Hemodynamic Assessment of Transgenic Mice In Vivo

        互联网

        432
        In the past few years there has been an explosive growth in the development of animal models of cardiovascular disease based on transgenic and gene-targeted strategies (1 ). Almost exclusively, the mouse has been the animal model employed in these studies owing to the relative ease with which its genome may be manipulated, short reproductive cycle, and low cost. Further advances now provide the ability to control gene expression in a temporal manner in the postnatal mouse heart (2 ) and, as described in other chapters of this monograph, the potential for assessing the feasibility and effectiveness of treating cardiovascular disease at the molecular genetic level through the use of gene therapy. Phenotypic analysis in the mouse though, has generally lagged behind the rapid advances in molecular biology owing to the unique challenges posed by the small size of the mouse heart (<6 mm length) and rapid heart rate (550–650 beats/min).
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序