CD32分子
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CD32 分子
CD32
常用单克隆抗体或代号： GIKM5,41H16(Fcg RⅡ)
主要表达细胞： Mac,G,M,B,Eo [NL]
分子质量(kDa)和结构： gp40(IgSF)
功 能： 吞噬,ADCC,B细胞活化负反馈
CD32
Aka Fc gamma RII
Low affinity receptor that binds to the Fc region of IgG immune complexes
If B cells are stimulated so that surface immunoglobulin receptors are coclustered with CD32 receptors, B cells do NOT proliferative and may undergo apoptosis instead of proliferation
Positive staining: macrophages, granulocytes, B cells, eosinophils, basophils, platelets
