Overview of Membrane Rafts

Transient lateral microdomains (rafts) in cell membranes have been postulated to perform a number of important functions in normal cells, and are also thought to be critically involved in several pathological conditions. However, there are still a number of fundamental unanswered questions concerning the composition, size, dynamics, and stability of membrane rafts. These questions are currently being addressed by a number of sophisticated biophysical, biochemical, and computational methodologies.