Effect of Lactobacilli Administration in the Vaginal Tract of Mice: Evaluation of Side Effects and Local Immune Response by Local Administration of Se

Lactobacilli are the predominant microorganisms in the vaginal tract of human and some homeothermic animals (1 ). They can maintain the ecological equilibrium of the tract by protecting against pathogenic microorganisms (2 ). In the last few years, there has been an increased tendency to use probiotic microorganisms to restore the ecological equilibrium and to protect against infections (3 ). This principle has been widely applied to the gastrointestinal tract (4 ). More recently, some other studies have reported the application of probiotics in different tracts, for example, the urogenital (5 ) or respiratory tract (6 ).