• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Transgenic Mice in Neurobiological Research

        互联网

        571
        The introduction of cloned genes into cells has greatly increased our knowledge of the factors that regulate the transcription of these genes and of the function of the proteins that they encode. Recently, techniques have been developed that allow the incorporation of cloned genes into the germline of mice (Gordon et al., 1980 9 ; Brinster et al., 1981 3 ; Costantini and Lacy, 1981 7 ). The generation of such transgenic animals has advanced our understanding of the elements involved in regulating tissue specificity and developmental expression of the incorporated genes. Additionally, these studies have yielded insight into the involvement of the transgenes in the physiology of the animal (Palmiter and Brinster, 1986 24 ). The application of this technique to genes of neurobiological interest can provide insights into the role specific genes play in the organization and function of the mammalian nervous system. In this article, we provide an overall view of the various aspects involved in generating transgenic animals and some of the potential applications of the technique to genes of neurobiological importance.
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序