• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Derivation of Human Parthenogenetic Stem Cell Lines

        互联网

        496
        Pluripotent stem cells (PSCs) derived from parthenogenetically activated human oocytes demonstrate the typical characteristics displayed by human embryonic stem cells (hESCs) including infinite division and in vitro and in vivo differentiation into cells of all germ lineages. Different activation techniques allow the creation of either human leukocyte antigen (HLA) heterozygous human parthenogenetic stem cell (hpSC) lines, which are HLA-matched/histocompatible with the oocyte donor, or HLA-homozygous hpSC lines, which may be histocompatible to significant segments of the human population. This immune-matching advantage, combined with the advantage of derivation from nonviable human embryos that originate from unfertilized parthenogenetically activated oocytes, makes hpSCs a promising source of PSCs for cell-based transplantation therapy. This chapter describes two approaches for the parthenogenetic activation of human oocytes, their cultivation to the blastocyst stage, and the subsequent derivation of PSC lines.
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序