Mitogenic Effects of Lectins on Epithelial Cells
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The specific binding of lectins to the carbohydrate moieties of glycoproteins and glycohpids on the cell surface has been
shown to result in a variety of signal transduction processes (1
,2
). One of the most dramatic effects of the interaction of lectins with cells is mitogenic stimulation, e.g., the triggering
of nondividing lymphocytes into a state of growth and proliferation (3
) which has led to the extensive and successful use of lectins in the analysis of events occuring during lymphocyte activation
and proliferation (4
,5
).
