CD15/CD15s/CD15u分子
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CD15/CD15s/CD15u 分子
CD15
常用单克隆抗体或代号： MY1,LeuM1
主要表达细胞： G,(M),RS [AS]
分子质量(kDa)和结构： Lewisx3FAL,X- hapten
功 能： 参与中性粒细胞粘附和吞噬
CD15s
常用单克隆抗体或代号： (唾液酸化CDl5)
主要表达细胞： G,M [AS]
分子质量(kDa)和结构： Sialyl Lewisx(sLex)
功 能： CD62E、CD62L、CD62P配体,白细胞粘附到En和Pt
CDl5u
常用单克隆抗体或代号： (硫酸化CDl5)
主要表达细胞： T，NK，En，G，M[CHol
功 能： 参与碳水化合物介导的细胞黏附
CD15
Aka LeuM1, Lacto-N-Fucopentose III ceramide
Recognizes Hapten X, a carbohydrate linked to cell membrane proteins of myelomonocytic cells
Positive staining (normal): myeloid cells (90%); activated B and T cells (including infectious mononucleosis); eosinophils stain intensely
Positive staining (disease): Reed-Sternberg cells, 20% of T cell lymphomas, 5% of B cell lymphomas, 50% of carcinomas
Negative staining: erythroid cells, platelets; ALL
Micro images: Reed-Sternberg cells-figure 3A, primary pulmonary Hodgkin’s lymphoma-figure 3A
CD15s
Aka Sialyl Lewis X; ligand for CD62P and CD62E
Positive staining (normal): granulocytes, macrophages
CD15u
Aka sulfated CD15
![Elab Fluor® 647 Anti-Human CD15/SSEA-1 抗体流式抗体[W6D3]](https://img1.dxycdn.com/p/s14/2024/0123/593/0610203543835069471.jpg!wh200)
