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结构基因组学

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HapMap assay-design protocols

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Chromosome (DNA) walking

This technique can be used to isolate overlapping DNA fragments starting with a previously cloned DNA fragment that maps near a gene of interest (dark red). The walk is continued until a clone containing the desired gene is identified. In this example, the chromosomal DNA fragments are cloned in λ pha ...

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Comparative Genomic Hybridization (CGH)

Protocol For the original protocol describing CGH see the article by Kallioniemi et al . For an example of how this technique has been utilized by the NCI Prostate Cancer Working Group see the section on Cell Lines.DNA RNAProteomicDNA sequence copy number changes throughout the genome in a single ...

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全基因组的比较基因组杂交技术介绍(Whole-Genome and Custom Fine-Tiling Array CGH)

Whole-Genome and Custom Fine-Tiling Array CGHComparative Genomic Hybridization (CGH) measures DNA copy number differences between a reference genome and your sample genome. NimbleGen offers two high-d ...

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