数据库

Abstract Table of Contents Materials Figures Literature Cited Abstract The computer program FAMS (Full Automatic Modeling System) performs homology modeling of protein structures by means of an algorithm

Abstract Table of Contents Materials Figures Literature Cited Abstract The Basic Protocol describes the use of GrailEXP, the latest version of the gene finding system from Oak Ridge National Laboratory. G

Abstract Table of Contents Materials Figures Literature Cited Abstract In this unit a protocol is described for predicting the structure of simple transmembrane a?helical bundles. The protocol is based on

Abstract Table of Contents Materials Figures Literature Cited Abstract The FASTA package provides a comprehensive set of similarity searching programs, similar to those provided by the BLAST package, and

Abstract Table of Contents Materials Figures Literature Cited Abstract GenMAPP (Gene MicroArray Pathway Profiler) is a free, stand?alone computer program designed for viewing and analyzing gene expression

Abstract Table of Contents Materials Figures Literature Cited Abstract The PEBBLE (Phylogenetics, Evolutionary Biology, and Bioinformatics in a moduLar Environment) application is a relative newcomer to t

Abstract Table of Contents Materials Figures Literature Cited Abstract The Basic Local Alignment Search Tool (BLAST) is one of the widest used and most useful applications in sequence?based bioinformatics

Abstract Table of Contents Literature Cited Abstract Cytokines, chemokines, and growth factors are soluble proteins produced by leukocytes and other cell types, which act as chemical communicators between cells and tissues within the body. These proteins mediate a number of

Abstract Table of Contents Figures Literature Cited Abstract RNAi is a novel genetic tool that is poised to revolutionize the study of genetics and gene networks. Use of this tool requires knowledge of the underlying mechanisms and applica

Abstract Table of Contents Figures Literature Cited Abstract This protocol describes the implementation and interpretation of THEMATICS, a simple computational predictor of functional information for proteins from the three?dimensional str

Abstract Table of Contents Figures Literature Cited Abstract This unit strictly focuses on data preparation within Spotfire. Microarray data exist in a variety of formats, which often depend on the particular array technology and detection

Abstract Table of Contents Figures Literature Cited Abstract Spotfire DecisionSite for Functional Genomics (referred to here as Spotfire) is a powerful data mining and visualization application with use in many disciplines. This unit provi

Abstract Table of Contents Figures Literature Cited Abstract Modern biology is on the verge of officially ushering in a new era in science with the completion of the sequencing of the human genome in April 2003. While often erroneously cal

Abstract Table of Contents Figures Literature Cited Abstract PROWL is a collection of tools for the identification of protein sequences, using input data derived from mass spectrometry. Experimental data from various types of mass spectrom

Abstract Table of Contents Figures Literature Cited Abstract Relational databases are designed to integrate diverse types of information and manage large sets of search results, greatly simplifying genome?scale analyses. Relational databas

Abstract Table of Contents Figures Literature Cited Abstract This unit assumes the reader is familiar with the Spotfire environment, has successfully installed Spotfire, and has uploaded and prepared data for analysis. It presents numerous

Abstract Table of Contents Figures Literature Cited Abstract Dynalign is a dynamic programming algorithm for the simultaneous prediction of the lowest?free?energy secondary structure common to two RNA sequences and the alignment of the two

Abstract Table of Contents Figures Literature Cited Abstract The VisANT tool, accessible from any recent Java?enabled browser, is a platform?independent, flexible, Web?enabled program for quick and simple construction, visualization, and a

Abstract Table of Contents Figures Literature Cited Abstract The wide availability and use of DNA microarrays has brought the power of whole?genome functional characterization to a large variety of research environments. Microarrays, howev

Abstract Table of Contents Figures Literature Cited Abstract Non?coding RNA (ncRNA) genes produce a functional RNA product, rather than a translated protein. The range and importance of such genes is only recently apparent, with known ncRN