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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Daudi
- 库存：
1x10^6/瓶
- 供应商：
上海酶研
- 肿瘤类型：
Burkitt淋巴瘤
- 细胞类型：
Daudi
- 品系：
Daudi
- 组织来源：
人Burkitt淋巴瘤细胞
- 相关疾病：
详询
- 物种来源：
人
- 免疫类型：
详询
- 细胞形态：
贴壁/悬浮
- 是否是肿瘤细胞：
是
- 器官来源：
人Burkitt淋巴瘤细胞
- 运输方式：
顺丰快递
- 年限：
5年
- 生长状态：
生长良好
- 规格：
瓶
Daudi、Daudi、Daudi细胞、Daudi细胞、Daudi人Burkitt淋巴瘤细胞
Cell line name Daudi
Synonyms DAUDI; NK-10A; NK-10a; NK 10a; NK10a; N; GM03190; GM3190; GM03190A; GM17346
Accession CVCL_0008
Resource Identification Initiative To cite this cell line use: Daudi (RRID:CVCL_0008)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: Human variation panel.
Part of: LL-100 blood cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Population: African; Kenyan.
Doubling time: 23.7 hours (PubMed=8847894); ~48 hours (DSMZ=ACC-78).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Microsatellite instability: Instable (MSI-low) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep antibody staining analysis.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Omics: Virome analysis using RNAseq.
Caution: TP53 mutation indicated incorrectly as being at c.637C>T in PubMed=2052620.
Misspelling: Duadi; Note=Occasionally.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x
Povey S., Jeremiah S., Arthur E., Steel M., Klein G.
Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy.
Ann. Hum. Genet. 44:119-133(1980)
PubMed=6935474; DOI=10.1093/jnci/66.2.239
Wright W.C., Daniels W.P., Fogh J.
Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.
J. Natl. Cancer Inst. 66:239-247(1981)
PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336
Benjamin D., Magrath I.T., Maguire R.T., Janus C., Todd-Kulikowsk H.D., Parsons R.G.
Immunoglobulin secretion by cell lines derived from African and American undifferentiated lymphomas of Burkitt's and non-Burkitt's type.
J. Immunol. 129:1336-1342(1982)
PubMed=6806672; DOI=10.1038/298474a0
Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.
Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
Nature 298:474-476(1982)
PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157
Westin E.H., Gallo R.C., Arya S.K., Eva A., Souza L.M., Baluda M.A., Aaronson S.A., Wong-Staal F.
Differential expression of the amv gene in human hematopoietic cells.
Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982)
PubMed=6186604; DOI=10.1007/BF00364753
de Preval C., Mach B.
The absence of beta 2-microglobulin in Daudi cells: active gene but inactive messenger RNA.
Immunogenetics 17:133-140(1983)
PubMed=11894933; DOI=10.1002/j.1460-2075.1983.tb01412.x; PMCID=PMC555120
Rosa F.M., Berissi H., Weissenbach J., Maroteaux L., Fellous M., Revel M.
The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon.
EMBO J. 2:239-243(1983)
PubMed=6200433; DOI=10.1007/BF00364762
Brodsky F.M.
A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.
Immunogenetics 19:179-194(1984)
PubMed=6231253; DOI=10.1002/ijc.2910330407
Ehlin-Henriksson B., Klein G.
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)
PubMed=6500159; DOI=10.1159/000163283
Gershwin M.E., Lentz D., Owens R.B.
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)
PubMed=6547209; DOI=10.1038/309592a0
Rabbitts T.H., Forster A., Hamlyn P.H., Baer R.
Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.
Nature 309:592-597(1984)
PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)
PubMed=6592381; DOI=10.1093/jnci/73.4.841
Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F., Lenoir G.M.
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)
PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.
Leuk. Res. 9:209-229(1985)
PubMed=2998993
Steel C.M., Morten J.E.N., Foster E.
The cytogenetics of human B lymphoid malignancy: studies in Burkitt's lymphoma and Epstein-Barr virus-transformed lymphoblastoid cell lines.
IARC Sci. Publ. 60:265-292(1985)
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文献和实验*发表【中文论文】请标注：由上海酶研生物科技有限公司提供；
*发表【英文论文】请标注：From Shanghai EK-Bioscience Biotechnology Co., Ltd.
、14.6μg/ml）低于Fab’对Raji、Daudi的IC50（45.9μg/ml、39.5μg/ml）。Fab'（50mg/kg，i.v.）和F（ab’）2(50mg/kg，i.p.）对荷瘤鼠瘤块体积的增长有抑制作用。结论 实现了直接在大肠杆菌中高效可溶性分泌表达有活性的抗CD20嵌合抗体Fab’和F（ab’）2的目的。Fab’适于显象，F（ab）2片段的抑制肿瘤生长活性明显高于Fab’，半衰期长于Fab’，更适于治疗。【关键词】B淋巴细胞瘤嵌合抗体Fab’片段 嵌合抗体F（ab）2片段CD20B淋巴细胞
LAK细胞和TIL活性的测定基本同NK活性测定方法。但所用靶细胞为对NK不敏感的肿瘤细胞，如Raji、Daudi或自体肿瘤细胞。常采用同位素法如51 Cr释放试验、发光免疫测定法及MTT比色法等。 在此介绍MTT比色法。 试剂及材料 1. 试剂：①四甲基偶氮盐（MTT）；②酸化异丙醇：含0.04mol/L HCl的异丙醇；③96孔细胞培养板。 2. 肿瘤细胞系： Raji细胞、Daudi细胞为B细胞性白血病细胞株；Molt-4为T细胞性白血病细胞，对LAK细胞敏感
Construction of RibonucleaseAntibody Conjugates for Selective Cytotoxicity
-resistant colon cancer cells in vitro and in vivo (7 ). Recently, RNase chemically conjugated to an antibody against CD22 was found to specifically kill Daudi lymphoma cells in cell culture at picomolar concentrations (IC50 , 10-50 pM) and to exhibit potent
技术资料