- ￥1300
- EK-Bioscience
- 国内
- A2709
- 2025年07月12日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 英文名：
K562
- 库存：
1x10^6/cell
- 供应商：
上海酶研
- 肿瘤类型：
无
- 细胞类型：
K562
- 品系：
K562
- 组织来源：
人慢性髓系白血病细胞；K562
- 相关疾病：
详询
- 物种来源：
人
- 免疫类型：
详询
- 细胞形态：
贴壁/悬浮
- 是否是肿瘤细胞：
否
- 器官来源：
人慢性髓系白血病细胞；K562
- 运输方式：
顺丰快递
- 年限：
5年
- 生长状态：
生长良好
- 规格：
瓶
K562细胞系、K562细胞株、K562人慢性髓系白血病细胞；K562
Cell line name K-562
Synonyms K562; K.562; K 562; KO; GM05372; GM05372E
Accession CVCL_0004
Resource Identification Initiative To cite this cell line use: K-562 (RRID:CVCL_0004)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: ENCODE project common cell types; tier 1.
Part of: LL-100 blood cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Part of: NCI-60 cancer cell line panel.
Population: Caucasian.
Doubling time: 17 hours (CelloPub=CLPUB00761); 47 hours (PubMed=25984343); 18 hours (PubMed=8142256); ~30-40 hours (DSMZ=ACC-10); 19.6 hours (NCI-DTP=K-562).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526; PubMed=23671654; Sanger).
Omics: Array-based CGH.
Omics: CTCF ChIP-seq epigenome analysis.
Omics: H2A.Z ChIP-seq epigenome analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K36me3 ChIP-seq epigenome analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K4me2 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: H3K79me2 ChIP-seq epigenome analysis.
Omics: H3K9ac ChIP-seq epigenome analysis.
Omics: H3K9me1 ChIP-seq epigenome analysis.
Omics: H3K9me3 ChIP-seq epigenome analysis.
Omics: H4K20me1 ChIP-seq epigenome analysis.
Omics: Pol2 ChIP-seq epigenome analysis.
Omics: CNV analysis.
Omics: Deep antibody staining analysis.
Omics: Deep exome analysis.
Omics: Deep proteome analysis.
Omics: Deep quantitative phosphoproteome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Fluorescence phenotype profiling.
Omics: Genome sequenced.
Omics: lncRNA expression profiling.
Omics: Metabolome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Omics: Virome analysis using proteomics.
Misspelling: K-652; Cosmic=1523829.
Misspelling: K652; Cosmic=1516632; Cosmic=2024372.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
PubMed=6996765; DOI=10.1182/blood.V56.3.344.344
Koeffler H.P., Golde D.W.
Human myeloid leukemia cell lines: a review.
Blood 56:344-350(1980)
PubMed=7194480; DOI=10.3181/00379727-166-41106
Lozzio B.B., Lozzio C.B., Bamberger E.G., Feliu A.S.
A multipotential leukemia cell line (K-562) of human origin.
Proc. Soc. Exp. Biol. Med. 166:546-550(1981)
PubMed=6954533; DOI=10.1073/pnas.79.7.2194; PMCID=PMC346157
Westin E.H., Gallo R.C., Arya S.K., Eva A., Souza L.M., Baluda M.A., Aaronson S.A., Wong-Staal F.
Differential expression of the amv gene in human hematopoietic cells.
Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982)
PubMed=6091813; DOI=10.1182/blood.V64.5.1059.1059
Palumbo A., Minowada J., Erikson J., Croce C.M., Rovera G.
Lineage infidelity of a human myelogenous leukemia cell line.
Blood 64:1059-1063(1984)
PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)
PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.
Leuk. Res. 9:209-229(1985)
PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30).
Leuk. Res. 9:549-559(1985)
PubMed=3856862; DOI=10.1073/pnas.82.6.1810; PMCID=PMC397362
Konopka J.B., Watanabe S.M., Singer J.W., Collins S.J., Witte O.N.
Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration.
Proc. Natl. Acad. Sci. U.S.A. 82:1810-1814(1985)
PubMed=3857109; DOI=10.1016/0165-4608(85)90101-3
Chen T.-R.
Modal karyotype of human leukemia cell line, K562 (ATCC CCL 243).
Cancer Genet. Cytogenet. 17:55-60(1985)
PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase.
Leuk. Res. 9:537-548(1985)
PubMed=3930277
Garson D., Dokhelar M.-C., Wakasugi H., Mishal Z., Tursz T.
HLA class-I and class-II antigen expression by human leukemic K562 cells and by Burkitt-K562 hybrids: modulation by differentiation inducers and interferon.
Exp. Hematol. 13:885-890(1985)
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验*发表【中文论文】请标注：由上海酶研生物科技有限公司提供；
*发表【英文论文】请标注：From Shanghai EK-Bioscience Biotechnology Co., Ltd.
mhy叶可 大家好，我是新手，第一次养细胞，恳请各位大虾给点关于培养K562以及K562/A02的建议。K562是悬浮细胞吗？还是半贴壁？半贴壁的话应该怎么换液？请各位老师不吝赐教，多谢，多谢。 yupingwang 悬浮细胞，离心后去上清，培养基重悬 mhy叶可 多谢，以后还要多多请教，呵呵 mhy叶可 请教楼上老师，k562/A02耐药细胞株培养时，怎么维持
hupengfei5566 各位大虾，我最近在做K562自噬方面的研究，但是几次Wstern Blot结果跑下来我发现一个很奇怪的现象，就是我的未处理组的K562细胞的自噬水平波动很大。按理，正常水平下自噬水平应该是比较低的，但我做的结果中第一次结果比较好，后几次发现未处理组的细胞自噬水平也很高，就好像诱导了一样，LC3-Ⅱ的表达水平比LC3-Ⅰ还要高，我在附件中放了3次的实验结果，第一孔就是我的未处理组。请高手指教。不知道大家有没有在试验中碰到过这个问题
人源造血干细胞 HSC 重建 NK 细胞杀伤及 ADCC 作用 随着效靶比的增加，NCG-hIL15 人源化小鼠重建 NK 细胞对于人慢性髓系白血病细胞 K562 的杀伤率也随之增加。并且当加入 Rituximab（靶向 CD20 抗体，主要通过抗体依赖性细胞介导的细胞毒作用 ADCC 杀伤 CD20+肿瘤细胞），Rituximab 抗体通过 NK 细胞介导的 ADCC 作用，对 Raji 细胞的杀伤作用进一步增强。 图 6. 基于 huHSC-NCG-hIL15 小鼠体内
技术资料