- 询价
- AtaGenix
- ATMA10313Mo
- 武汉
- 2025年07月14日
- WB:1:1000 - 1:3000;ELISA:1:1000-1:3000;ICC:1:1000.
- Mouse
- 人
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
普健生物（武汉）科技有限公司
- 库存：
100
- 级别：
科研试剂
- 目录编号：
ATMA10313Mo
- 克隆性：
单克隆
- 保质期：
12个月
- 抗体英文名：
Anti SARS-CoV-2(2019-nCoV) S protein RBD monoclonal antibody(F3C10)
- 抗体名：
Anti SARS-CoV-2(2019-nCoV) S protein RBD monoclonal antibody(F3C10)
- 宿主：
Mouse
- 适应物种：
人
- 免疫原：
Recombinant SARS-CoV-2 S Protein RBD
- 亚型：
IgG 1
- 形态：
Liquid
- 应用范围：
WB:1:1000 - 1:3000;ELISA:1:1000-1:3000;ICC:1:1000.
- 保存条件：
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
- 浓度：
0.98mg/ml
- 规格：
100ug
产品名称（Product name）
Anti SARS-CoV-2(2019-nCoV) S protein RBD monoclonal antibody(F3C10)
描述（description）
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) RBD protein.
Accession #
P0DTC2
别名（Alternative names)
S glycoprotein,E2,Peplomer protein,Spike protein S1
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性（Spcificty）
Recognizes SARS-CoV-2 S Protein RBD
亚型（Isotype）
IgG 1
宿主（Host）
Mouse
克隆性（Clonality）
Monoclonal
克隆号（Clone No.）
F3C10
偶连物（Conjugation）
Unconjugated
种属反应性（Species reactivity）
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验（Tested applications）
WB;ELISA;ICC.
免疫原（Immunogen）
Recombinant SARS-CoV-2 S Protein RBD
活性（Bioactivity）
背景（Background）
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
产品性能（ Product performance）
状态（Form）
Liquid
储存溶液（Buffer）
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度（Concentration）
0.98mg/ml
分子量（MW）
142kDa
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文献和实验neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Preprint at bioRxiv 11: Lynch, KL et al. (2020) Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity. Preprint
Antibody-Directed Enzyme-Prodrug Therapy
of hybridoma technology in the 1980s, monoclonal antibodies either alone or linked to a wide range of therapeutic agents such as radionuclides, drugs, toxins, enzymes, and growth factors have been used for diagnosis and therapy of diseases, particularly cancer
Methods to Detect Protein Glutathionylation
) Anti‐GSH mouse monoclonal primary antibody (ViroGen) Protein A/G agarose beads Phosphate‐buffered
