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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
K-Ras
- 应用范围:
WB, IHC
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat
- 保质期:
12个月
- 库存:
88
- 供应商:
上海博尔森生物科技有限公司
- 克隆性:
Rabbit polyclonal Antibody
- 保存条件:
详见说明书
- 形态:
详见说明
- 亚型:
IgG
- 免疫原:
The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-200
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2500.0 |
抗体的概念:
抗体的结构图:
抗体的分类:
1.从制备方式的角度,分为多抗和单抗:
2.从实验应用的角度,分为一抗和二抗。
单抗和多抗的区别:
| 多克隆抗体 |
单克隆抗体 |
| 制备成本低廉 |
制备成本高昂 |
| 制备技能要求不高 |
应用技术之前需接受专门培训 |
| 制备速度较快 |
需要较长的时间制备杂交瘤细胞 |
| 产生大量非特异性抗体 |
产生大量特异性抗体 |
| 识别任一抗原上的多个表位 |
仅识别一个抗原上的单一表位 |
| 批次间可能存在差异 |
制得的杂交瘤细胞为持续且可再生产的单克隆抗体来源 |
| - |
批次间无差异或差异较小 |
一抗和二抗的关系:
抗体的应用:
抗体的用途:
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文献和实验Detection of K-ras Mutations by a Microelectronic DNA Chip
. These potential molecular tumor markers are essential not only for the diagnosis, prognosis, or the follow-up of the disease but also for the management of therapy (1 ,2 ). Particularly, the K-ras protooncogene is altered, by point mutations within codons
A Novel Method for the Production of Fully Modified K-Ras 4B
post-translationally modified proteins in bacterial expression systems is often problematic. Here, we describe a novel recombinant approach to prepare human K-Ras 4B, a protein that is post-translationally farnesylated
Analysis of K-RAS and P53 Mutations in Sputum Samples
Mutations in the P53 tumor suppressor gene and the K-RAS oncogene have frequently been found in sputum and bronchoalveolar lavage (BAL) samples of lung cancer patients, and also in samples from patients prior to presenting clinical symptoms
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