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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
RAP1
- 应用范围:
WB
- 宿主:
Rabbit
- 适应物种:
Human
- 保质期:
12个月
- 库存:
88
- 供应商:
上海博尔森生物科技有限公司
- 克隆性:
Rabbit polyclonal Antibody
- 保存条件:
详见说明书
- 形态:
详见说明
- 亚型:
IgG
- 免疫原:
The antiserum was produced against synthesized peptide derived from human RAP1. AA range:203-252
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2500.0 |
抗体的概念:
抗体的结构图:
抗体的分类:
1.从制备方式的角度,分为多抗和单抗:
2.从实验应用的角度,分为一抗和二抗。
单抗和多抗的区别:
| 多克隆抗体 |
单克隆抗体 |
| 制备成本低廉 |
制备成本高昂 |
| 制备技能要求不高 |
应用技术之前需接受专门培训 |
| 制备速度较快 |
需要较长的时间制备杂交瘤细胞 |
| 产生大量非特异性抗体 |
产生大量特异性抗体 |
| 识别任一抗原上的多个表位 |
仅识别一个抗原上的单一表位 |
| 批次间可能存在差异 |
制得的杂交瘤细胞为持续且可再生产的单克隆抗体来源 |
| - |
批次间无差异或差异较小 |
一抗和二抗的关系:
抗体的应用:
抗体的用途:
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文献和实验Rap1 and Integrin Inside-Out Signaling
In leukocytes, integrins play important roles in adhesive interactions with endothelium, antigen-presenting cells, and effector functions such as cytotoxicity. This chapter describes methods to study Ras proximity 1 (Rap1), a signaling
Fluorescence Microscopy Study of Rap1 Subcellular Localization
The Ras-related GTPase Rap has been implicated in multiple cellular functions. In particular, Rap1 is a crucial regulator of both inside-out integrin activation and outside-in E-cadherin-mediated signaling. Thus, Rap1
Cell-Free Assay System for Ras- and Rap1-Dependent Activation of MAP-Kinase Cascade
It is well-established that Ras activates the mitogen-activated protein (MAP) kinase cascade consisting of MAP kinase, extracellular signal-regulated kinase (ERK), ERK kinase (MEK), and MEK kinase in mammals (for reviews, see refs. 1 –
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