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文献和实验Serum Low-Molecular-Weight Protein Fractionation for Biomarker Discovery
, and cerebrospinal fluid. Unfortunately, discovering and validating protein biomarkers are hindered by the presence of high-molecular-weight proteins, such as serum albumin and immunoglobulins, which comprise 90% of the proteins present in these samples. High
Targeting Cancer with Small-Molecular-Weight Kinase Inhibitors
Protein and lipid kinases fulfill essential roles in many signaling pathways that regulate normal cell functions. Deregulation of these kinase activities lead to a variety of pathologies ranging from cancer to inflammatory diseases, diabetes
Preparation of the Low Molecular Weight Serum Proteome for Mass Spectrometry Analysis
for immune-related low molecular weight serum biomarkers. One such method in the field of proteomics is to divide the sample proteome into groups based on the size of the protein, analyze each group, and mine the data for statistically significant items
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