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- 2025年07月14日
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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期：电询
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MedChemExpress LLC
- CAS号：
835876-32-9
- 规格：
250 μg
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Platensimycin
CAS No. : 835876-32-9
MCE 国际站：Platensimycin
产品活性：Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
研究领域：Anti-infection
作用靶点：Antibiotic | Bacterial
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文献和实验Srinivas Kodali Andrew Galgoci Sheo Singh Dr. Jun Wang Dr., jun_wang2@merck.com, Merck Research Laboratories Related Journal & Article InformationManuscript: 2006-01-00990C Journal: Nature Article Title: Platensimycin is a selective FabF inhibitor
Gel-elongation assay for type II fatty acid synthesis
Related Journal & Article Information Manuscript: 2006-01-00990C Journal: Nature Article Title: Platensimycin is a selective FabF inhibitor with potent antibiotic properties
Gel-elongation assay for type II fatty acid s
Related Journal & Article Information Manuscript: 2006-01-00990C Journal: Nature Article Title: Platensimycin is a selective FabF inhibitor with potent antibiotic
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