Xeruborbactam,2170834-63-4

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Xeruborbactam

CAS No. : 2170834-63-4

MCE 国际站：Xeruborbactam

产品活性：Xeruborbactam (QPX7728) 是一种有效、超广谱的硼酸 β-内酰胺酶 (beta-lactamase) 抑制剂。Xeruborbactam 在纳米摩尔范围内抑制丝氨酸和金属 β-内酰胺酶。

研究领域：Anti-infection

作用靶点：Bacterial

In Vitro: Xeruborbactam is a potent inhibitor of Class D carbapenemases from A. baumannii.
Xeruborbactam is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam.
The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate Xeruborbactam is a useful inhibitor for use with multiple beta-lactam antibiotics.

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