Cearoin,52811-37-7

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Cearoin

CAS No. : 52811-37-7

MCE 国际站：Cearoin

产品活性：Cearoin 通过促进 ROS 产生和激活 ERK 来增强自噬 (autophagy) 和诱导细胞凋亡(apoptosis)。

研究领域：Autophagy  |  Metabolic Enzyme/Protease  |  Immunology/Inflammation  |  NF-κB  |  MAPK/ERK Pathway  |  Stem Cell/Wnt  |  Apoptosis

作用靶点：Autophagy  |  Reactive Oxygen Species  |  ERK  |  Apoptosis

In Vitro: Cearoin (10-80 μM) induces cell death in a dose-dependent manner.
?Cearoin (10-80 μM) increases the phosporylation of ERK in SH-SY5Y cells.
?Cearoin (5-80 μM) increases the conversion of LC3B-I to LC3B-II in SH-SY5Y cells. The expression of LC3B-II is a good marker for autophagosome formation in the autophagy process.

相关产品：Natural Product Library Plus  |  Bioactive Compound Library Plus  |  MG-132  |  Doxorubicin hydrochloride  |  Bafilomycin A1  |  LY294002  |  Tamoxifen  |  Paclitaxel  |  Y-27632  |  Acetylcysteine  |  Angiotensin II human  |  2-Deoxy-D-glucose  |  Staurosporine  |  H2DCFDA  |  SB-431542  |  Actinomycin D  |  Deferoxamine mesylate  |  Bortezomib  |  5-Fluorouracil  |  Trametinib  |  Sorafenib  |  Oxaliplatin  |  Gemcitabine  |  Temozolomide  |  Rotenone  |  Mdivi-1  |  Elesclomol  |  Ruxolitinib  |  Decitabine  |  SP600125  |  MK-2206 dihydrochloride  |  Etoposide

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds