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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
DBCO-Maleimide
- 供应商:
靶点科技
- 规格:
25 mg
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文献和实验and stability. Here we elaborate detailed protocols using maleimide-based chemistry for the conjugation to reduce hinge disulfides in antibodies by several cytotoxic drugs. We present a method for the initial characterization of the reduction/alkylation reaction
NAR新突破:CliPEdit调控RNA功能与m⁶A甲基化,翌圣试剂助力
试剂 BANEIC(含双叠氮基团与光裂解硝ji苯基团)和 t-DBCO(三价DBCO交联剂),通过三步调控实现 ON → OFF → ON 的RNA功能切换: Step1. ON 态:BANEIC修饰RNA:使其同时具备—点击化学(click chemistry)可连接性(含叠氮基)、光可裂解性(含硝ji苯基团)。修饰后 gRNA 功能正常,靶向写入 m⁶A; Step2. OFF态:加入 t‑DBCO,通过 SPAAC 点击反应交联 gRNA,空间位阻使其彻底失活,m⁶A甲基化关闭; Step
How Do I make an Antibody against a Peptides
If your peptide is synthesized with a terminal cysteine residue (i.e., a free sulfhydryl group, -SH), you can use any maleimide-activated carrier protein to create an immunogen. One-step chemical reactions are easy with Pierce Sulfo-SMCC Pre
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