Circadian Locomoter Output Cyc

产品名称：Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody-Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody

产品货号：abx004307

产品规格：20ul#50ul#100ul#200ul

应用类型：WB, IHC

保存建议：Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody-Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：CLOCK Antibody is a Rabbit Polyclonal antibody against CLOCK. The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

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关键词：Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody，Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody，待更新