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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温
- 库存：
现货
- 供应商：
联硕生物
- CAS号：
50-44-2
- 规格：
1瓶
一般描述
6-巯基嘌呤（6-MP）为嘌呤类似物，常用于治疗儿童急性淋巴细胞白血病。也广泛用于治疗皮质类固醇依赖性炎症性肠病（IBD）或克罗恩氏病（Crohn′s disease）。 [1][2]
应用
6-巯基嘌呤（6-MP）可作为分析参考标准品，通过高效液相色谱法（HPLC）技术测定生物样品[3][4] 中的分析物。
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文献和实验Development and validation of an HPLC method for the rapid and simultaneous determination of 6-mercaptopurine and four of its metabolites in plasma and red blood cells
Hawwa AF, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(2), 401-409 (2009)
Human Peripheral Blood Mononuclear Cell Preparation
in 1 to 2 ml of PBS, and transfer the latter to a fresh tube (to avoid contaminating the solution with the platelets that are adhering to the sides of the tube).7. Bring the cell suspension to a final volume of 50 ml and gently overlay 12.5 ml onto the Ficoll
Cell Staining for Senescence-Associated beta-Galactosidase (SA-beta-Gal) Activity
is VERY important pH 6.0 PBS pH 7.2 2.7 mM KCl 4.3 mM Sodium Phosphate Dibasic (Na2HPO4) 1.8 mM Potassium Phosphate Monobasic (KH2PO4) 137 mM NaCl Tips 1. CAUTION! This substance is a biohazard. Consult this agent's MSDS for proper handling
out the MSDS to verify the precautions you should take. A solution of PEG 400 is recommended for first aid. Phenol is both a systemic and local toxic agent. You want to visit the medical center. If you''re in a hurry, you can shorten the protocol
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