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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide amino acids: 737-751 of human APP UniProt: P05067 or 85-99 of the C99 generated by secretases.
- 形态:
Immunogen affinity purified in PBS. Contains 0.02% sodium azide.
- 保存条件:
Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- 克隆性:
Polyclonal
- 适应物种:
Human, mouse, rat
- 供应商:
Agrisera
- 宿主:
Rabbit
- 应用范围:
Western blot (WB)
- 靶点:
Anti-APP | Amyloid Precursor Protein (C-term)
- 抗体英文名:
Anti-APP | Amyloid Precursor Protein (C-term)
- 抗体名:
Anti-APP | Amyloid Precursor Protein (C-term)
- 规格:
100 µg
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文献和实验Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins
including fly (4 ), nematode (5 ), and fish (6 ). In mammals, two APP-like genes, amyloid precursor-like protein 1 (APLP1) and 2 (APLP2), have been isolated (7 ,8 ). The amino acid sequences of these APP family proteins are highly conserved, especially
Using an Amyloid Precursor Protein (APP) Reporter to Characterize α-Secretase
Human genetic studies suggest decreasing amyloid peptide (Aβ) levels in the brain could alter the course of Alzheimer’s disease (AD) (1 -4 ). Proteolytic cleavages govern the level of Aβ generated from the amyloid precursor protein (APP). β
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