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- 详细信息
- 文献和实验
- 技术资料
- 库存:
99
- 英文名:
SARS-CoV-2 (2019-nCoV) Spike RBD(F377L)-His Recombinant Protein
- 保质期:
12个月
- 供应商:
北京义翘神州科技股份有限公司
- 保存条件:
-20℃ to -80℃
- 规格:
100 µg
纯度> 85 % as determined by SDS-PAGE.
内毒素< 1.0 EU per μg protein as determined by the LAL method.
生物活性Testing in progress
蛋白构建A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike RBD(F377L)-His Recombinant Protein (YP_009724390.1) (Arg319-Phe541(F377L)) was expressed with a polyhistidine tag at the C-terminus.
NP No.YP_009724390.1
表达宿主HEK293 Cells
种属2019-nCoV
预测 N 端Arg319
分子量The recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(F377L)-His Recombinant Protein consists of 234 amino acids and predicts a molecular mass of 26.5 kDa.
缓冲液Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
运输方式In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
稳定性 & 储存条件Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
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文献和实验日前,北京大学生命科学学院魏文胜课题组在 Cell 杂志上在线发表题为“Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants”的研究论文。 魏文胜团队首先建立了体外高效制备高纯度环状 RNA 的技术平台,针对新型冠状病毒及其变异株,设计了编码新冠病毒刺突蛋白(Spike)受体结构域(RBD)的环状 RNA 疫苗。 该项研究中制备的针对新冠病毒德尔塔变异株的环状 RNA 疫苗(circRNARBD
5位院士为代表,超12篇CNS大作,5月新冠研究汇总——全方位围攻新冠病毒,值得收藏
从 8 名 SARS-CoV-2 感染者的单个 B 细胞中分离并鉴定了 206 株 RBD 特异性单克隆抗体,并鉴定出具有抗 SARS-CoV-2 中和活性的抗体,这种中和活性与它们与 ACE2 竞争 RBD 结合的能力有关9。 此外,复旦大学基础医学院应天雷团队在抗新冠抗体药物研发方面也取得了重要的进展,该团队发现了一系列抗新冠全人源纳米抗体,可靶向新冠病毒受体结合区上的五类不同表位。该成果于 5 月 14 日在 Cell Host & Microbe 上发表,题为
许石正丽的这篇综述可以解释:为什么每次冠状病毒疫情都会打得我们措手不及?
上,给专业疾控机构充分赋权,简化行政审批,完善立法,健全针对重大突发性传染疾病的联动响应机制,并设立危机应对的常备队伍。在国民教育层面,加大健康教育和全民疾病科普,用实际行动提升人民对政府和科研机构的信任。参考文献1 Cui, J., Li, F. & Shi, Z.-L. Origin and evolution of pathogenic coronaviruses. Nature Reviews Microbiology 17, 181 - 192, doi:10.1038 /s41579
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