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- 详细信息
- 文献和实验
- 技术资料
- 库存:
99
- 英文名:
SARS-CoV-2 (2019-nCoV) Spike RBD(P384L)-His Recombinant Protein
- 保质期:
12个月
- 供应商:
北京义翘神州科技股份有限公司
- 保存条件:
-20℃ to -80℃
- 规格:
100 µg
纯度> 95 % as determined by SDS-PAGE.
内毒素< 1.0 EU per μg protein as determined by the LAL method.
生物活性Testing in progress
蛋白构建A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike RBD(P384L)-His Recombinant Protein (YP_009724390.1) (Arg319-Phe541(P384L)) was expressed with a polyhistidine tag at the C-terminus.
NP No.YP_009724390.1
表达宿主HEK293 Cells
种属2019-nCoV
预测 N 端Arg319
分子量The recombinant SARS-CoV-2 (2019-nCoV) Spike RBD(P384L)-His Recombinant Protein consists of 234 amino acids and predicts a molecular mass of 26.6 kDa.
缓冲液Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
运输方式In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
稳定性 & 储存条件Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
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文献和实验日前,北京大学生命科学学院魏文胜课题组在 Cell 杂志上在线发表题为“Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants”的研究论文。 魏文胜团队首先建立了体外高效制备高纯度环状 RNA 的技术平台,针对新型冠状病毒及其变异株,设计了编码新冠病毒刺突蛋白(Spike)受体结构域(RBD)的环状 RNA 疫苗。 该项研究中制备的针对新冠病毒德尔塔变异株的环状 RNA 疫苗(circRNARBD
感染新冠后为什么会眼睛痛?Nature 子刊揭示新冠病毒会引起视网膜炎症、影响深度知觉
新冠感染往往会引起发烧、咳嗽、肌肉酸痛等症状,这些症状通常伴随着感染的结束而逐渐消失。但是,也有少部分治愈者会表现出轻度或重度的后遗症,常见的有脑雾、嗅觉味觉失灵等问题。 同时,也有不少 COVID-19 患者在感染时会出现眼睛疼痛、发炎的症状,但是关于 SARS-CoV-2 对眼睛的影响仍然缺乏科学认知。 2022 年 12 月 12 日,一项发表在 Nature Communications 的研究论文 Ocular tropism of SARS-CoV-2 in animal
能否平息导致 COVID-19 患者死亡的炎症因子风暴。 saRNA 工作原理 (MiNA Therapeutics 公司官网) 结语 COVID-19 潜在治疗和预防策略基本围绕阻止 SARS-CoV-2 进入细胞、干扰病毒复制、抗病毒药物、疫苗和抑制过度免疫反应等重要节点展开。 以上这两项技术是用于肿瘤治疗的技术,但迁移至新冠病毒治疗策略。涉及核酸适体的筛选和构建,推测是以化学合成的病毒寡核苷酸文库中或来自病毒毒株的S蛋白、S蛋白上的多肽
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