PF-6683324,1799788-94-5

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PF-6683324

CAS No. : 1799788-94-5

MCE 国际站：PF-6683324

产品活性：PF-6683324 (Trk-IN-4) 是一种有效的 pan-Trk 抑制剂，抑制 TrkA，TrkB 和 TrkC 细胞，IC₅₀ 分别为 1.9 nM，2.6 nM 和 1.1 nM。具有抗痛觉过敏作用。

研究领域：Neuronal Signaling  |  Protein Tyrosine Kinase/RTK

作用靶点：Trk Receptor

In Vitro: PF-6683324 (Trk-IN-4) (Compound 10b) exhibits superb Trk selectivity with >95% inhibition of TrkA and >40% inhibition of only 1 other kinase VEGFR2 (cell-based assay for VEGFR2 IC₅₀>5 μM).

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