3-Phenyltoxoflavin,32502-63-9

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3-Phenyltoxoflavin

CAS No. : 32502-63-9

MCE 国际站：3-Phenyltoxoflavin

产品活性：3-Phenyltoxoflavin 是 Toxoflavin 的衍生物，是一种 Hsp90 抑制剂，抑制 Hsp90-TPR2A 之间相互作用的 K_d 值为 585 nM。3-Phenyltoxoflavin 具有抗癌活性。

研究领域：Cell Cycle/DNA Damage  |  Metabolic Enzyme/Protease

作用靶点：HSP

In Vitro: 3-Phenyltoxoflavin (1 nM-100 μM; 4 d) inhibits BT474 cells proliferation in a concentration-dependent manner, with an IC₅₀ of 690 nM.
3-Phenyltoxoflavin (0.56 nM-100 μM; 2 h) competes with biotinylated Hsp90 peptide for its binding to TPR2A in a dose-dependent manner.

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