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文献和实验A(H3N2) and A(H1N1) viruses, including the 2009 pandemic H1N1 strain. The limited pharmaceutical options currently available for control of influenza infections underscore the critical need for surveillance on NAI susceptibility of influenza viruses
Genetic Engineering of Live Attenuated Influenza Viruses
The first live attenuated influenza vaccine (LAIV) was licensed in the USA in 2003; it is a trivalent vaccine composed of two type A (H1N1 and H3N2) and one type B influenza virus each at 107 fluorescent focus units (FFU). Each influenza
PCR for the Detection of Influenza Viruses in Clinical Material
). Influenza A viruses are further divided into subtypes H1N1, H2N2 and H3N2, based on differences in the hemagglutinin (HA) and neuraminidase (NA) genes. The ability of influenza viruses to undergo antigenic change in HA and NA enables the virus to evade
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