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文献和实验Structural Determinants of Folate and Antifolate Membrane Transport by the Reduced Folate Carrier
Besides its important role in folate homeostasis, membrane transport is a critical determinant of the antitumor activities of anti folate therapeutics used in cancer chemotherapy, such as methotrexate (MTX) and an exciting new generation
Sorting of Bacterial Lipoproteins to the Outer Membrane by the Lol System
on either the inner or the outer membrane. The Lol system is responsible for the transport of lipoproteins to the outer membrane. The Lol system comprises an inner-membrane ABC transporter LolCDE complex, a periplasmic carrier protein, LolA, and an outer
Two-dimensional polyacrylamide gel electrophoresis of membrane proteins
across a pH gradient. The pH gradient necessary for the separation according to isoelectric point (pL) is usually established by electrophoresing carrier ampholytes prior to and/or concomitantly with the sample. The second dimension is usually a separation
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