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文献和实验Congenital Heart Disease: Molecular Diagnostics of Supravalvular Aortic Stenosis
Supravalvular aortic stenosis (SVAS) is a congenital heart disease that can occur as an iso-lated autosomal-dominant condition or as part of the developmental disorder Williams-Beuren syndrome (WBS) and is caused by heterozygous genetic
Quantitative Analysis of Atherosclerotic Lesion Composition in Mice
Comparative quantitation has become an increasingly desirable tool in determining compositional differences of aortic plaque lesion in transgenically altered mice. To this end, methodology has been developed to identify lipid, cellularity
Quantitative Determination of Collagen Cross-links
-fibrillar cross-links, and are tissue rather than species specific. We describe the determination of these cross-links in detail. Elastin is also stabilised by cross-linking based on oxidative deamination of most of its lysine residues to yield
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