biochain特约代理商|D1255811 Genomic

Transfer of Human Chromosome 3 to an Ovarian Carcinoma Cell Line Identifies Regions Involved in Ovarian Cancer

is schematically outlined in Fig. 1. MMCT was used successfully with cell lines from tumors of different histotypes to detect chromosomal regions containing tumor suppressor genes and to identify chromosomes involved in the tumorigenic phenotype.

Utilizing DNA Mutations to Trace Epithelial Cell Lineages in Human Tissues

of cells with the same ancestry. In normal epithelium, nonpathogenic mitochondrial DNA mutations have proven useful. In premalignant and malignant disease, genomic DNA mutations within tumor suppressor genes or oncogenes can be used to trace the spread

Authentication of Cancer Cell Lines by DNA Fingerprinting

on the detection of chromosomal markers, it was convincingly demonstrated that multiple cell lines under active investigations were actually derived from one source, namely the HeLa cell line (5 ). Furthermore, cross-contamination among established cell lines