abbexa特约代理商|abx250565 Human In

10.21 华中科技大学 Nature 子刊揭示精母细胞中逆转录转座子沉默的分子机制

大学和汉阳大学的研究人员发现 G 蛋白α- 13（Gα13）的表达在糖尿病小鼠和人类的肝脏中下降了。在小鼠中仅剔除肝脏中的 Gna13 基因可导致全身性葡萄糖耐受不良。本研究表明小鼠中的全身胰岛素抵抗是由 Gα13 下调导致的肝脏中 ITIH1 过度分泌引起的，这可通过 ITIH1 中和加以逆转。这些发现可能有助于开发治疗代谢疾病的新策略。原文检索：Overproduction of inter-α-trypsin inhibitor heavy chain 1 after loss of Gα13

Differentiation of Human Embryonic Stem Cells to Cardiomyocytes on Microcarrier Cultures

4 ) MAP kinase inhibitor SB203580 (Sigma‐Aldrich, cat. no. S8307), previously dissolved in DMSO at 5 mM (see recipe ) hESC (HES‐3 cell line from ES International, and H1

Screening for Aging-Dependent Point Mutations in mtDNA

samples for the identified mutations. Fig. 2.  Main control region of human mtDNA. This region contains the initiation sites for rDNA (I H 1), whole heavy-strand (P H 2) and light-strand transcription (I