Anti-TNFSF10 Polyclonal Antibody

Anti-TNFSF10 Polyclonal Antibo

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  • ¥960 - 1600
  • Solarbio已认证
  • 北京
  • 2025年07月09日
  • Rabbit
  • Human Mouse Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human TNFSF10

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at -20°C. Avoid freeze / thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human Mouse Rat

    • 目录编号

      K003248P

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 靶点

      TNFSF10

    • 抗体英文名

      Anti-TNFSF10 Polyclonal Antibody

    • 抗体名

      APO2L;Apo-2L;CD253;TL2;TNLG6A;TRAIL

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    产品简介
    单位
    英文名称 Anti-TNFSF10 Polyclonal Antibody
    别名 APO2L;Apo-2L;CD253;TL2;TNLG6A;TRAIL
    宿主 Rabbit
    稀释比例 WB 1:500-2000. IHC 1:50-200.
    Gene ID 8743
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    Swiss Prot P50591
    蛋白分子量 33kDa
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    亚细胞定位 Membrane Single-pass type II membrane protein
    免疫原 Recombinant protein of human TNFSF10
    亚型 IgG
    性状 液体
    纯化方法 Affinity purification
    背景资料 The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Public Immunogen Range Recombinant protein of human TNFSF10
    克隆类型 Polyclonal Antibody
    交叉反应 Human Mouse
    应用 WB IHC
    规格 50ul 100ul

    备注:
    以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
    These protocols are for reference only. Solarbio does not independently validate these methods.
    温馨提示:
    使用前请离心。如有问题请及时联系我们。
    Quick spin before use. If you have any questions, please contact us.
    实验图
    Anti-TNFSF10 Polyclonal Antibo
    Western blot analysis with TNFSF10 antibody diluted at 1:1000
    Anti-TNFSF10 Polyclonal Antibo
    Immunohistochemistry of paraffin-embedded colon carcinoma(hu) using TNFSF10 antibody at dilution of 1:200 (x40 lens).
    Anti-TNFSF10 Polyclonal Antibody
    宿主 Rabbit
    别名 APO2L;Apo-2L;CD253;TL2;TNLG6A;TRAIL
    稀释比例 WB 1:500-2000. IHC 1:50-200.
    蛋白分子量 33kDa
    Gene ID 8743
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human TNFSF10
    性状 液体
    Public Immunogen Range Recombinant protein of human TNFSF10
    亚细胞定位 Membrane Single-pass type II membrane protein
    Swiss Prot P50591
    克隆类型 Polyclonal Antibody
    背景资料 The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    应用    WB IHC
    规格    50ul    100ul

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