- ￥960 - 1600
- Solarbio
- 北京
- K107715P
- 2025年07月14日
- IHC
- Rabbit
- Human Mouse Rat
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- 详细信息
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Cytoplasm Nucleus
- 适应物种：
Human Mouse Rat
- 保质期：
现询客服
- 抗原来源：
现询客服
- 库存：
99
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
现询客服
- 靶点：
HMGCR
- 抗体英文名：
Anti-HMGCR Polyclonal Antibody
- 抗体名：
HMG CoA reductase, HMGCR
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
产品简介
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Immunohistochemistry of paraffin-embedded Human breast cancer with HMGCR antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded Human prostate cancer with HMGCR antibody diluted at 1:100
| 英文名称 | Anti-HMGCR Polyclonal Antibody |
| 宿主 | Rabbit |
| 别名 | HMG CoA reductase； HMGCR |
| 稀释比例 | IHC 1:50-200. |
| 蛋白分子量 | 92/99kDa |
| Gene ID | 3156 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HMGCR |
| 亚细胞定位 | Cytoplasm Nucleus |
| Swiss Prot | P04035 |
| 背景资料 | HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene |
| Public Immunogen Range | 486-835aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Rat Mouse |
| 应用 | IHC |
| 规格 | 50ul 100ul |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Immunohistochemistry of paraffin-embedded Human breast cancer with HMGCR antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded Human prostate cancer with HMGCR antibody diluted at 1:100
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Anti-HMGCR Polyclonal Antibody
￥960 - 1600
