Anti-Norepinephrine Transporter; 100 μg产品图

Anti-Norepinephrine Transporte

r; 100 μg
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  • 询价
  • AB2234
  • 2026年08月16日
  • Western Blotting
  • Rabbit
  • Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Western Blotting

    • 宿主：

      Rabbit

    • 抗原来源：

      0

    • 适应物种：

      Rat

    • 库存：

      大量

    • 是否单克隆：

      2

    • 规格：

      100 μg

    Product Images

    Western Blot Analysis:
    Nonstimulated PC12 lysate was resolved by electrophoresis, transferred to PVDF and probed with anti-Norepinephrine Transpo...
    Species Reactivity Key Applications Host Format Antibody Type
    R WB Rabbit Purified Polyclonal Antibody
    Description:
    Anti-Norepinephrine Transporter
    Background Information:
    The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. In the CNS, norepinephrine is involved in a number of physiological responses including mood, sleep regulation, alertness and arousal, both cognitive and non-cognitive expression of behaviors, and control of the endocrine and autonomic nervous systems. Peripherally, norepinephrine is present in sympathetic nerve endings and has full control of the sympathetic nervous system. Certain antidepressant medications act to raise norepinephrine, such as the SNRIs and the tricyclic antidepressants (TCAs). In essence, these medications prevent the norepinephrine transporter from serving its purpose. Norepinephrine therefore remains in the synapse longer, allowing it to reach more normal levels. Since the norepinephrine transporter is also thought to transport dopamine to some extent, SNRIs would also raise dopamine levels in the synapse.
    Alternate Names:
    • Norepinephrine transporter
    • noradrenaline transporter
    • solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
    • solute carrier family 6 (neurotransmitter transporter, norepinephrine), member 5
    • solute carrier family 6 member 2
    Specificity:
    Cat. # AB2234 recognizes norepinephrine transporter
    Key Applications:
    Western Blotting
    Species Reactivity:
    Rat
    Species Reactivity Note:
    Rat. May react with human, mouse, dog and cow based on sequence homology. Reactivity with other species has not been determined.
    Immunogen:
    Synthetic Linear Peptide
    Molecular Weight:
    ~69 kDa
    Control:
    PC12 lysate.
    Presentation:
    Purified in 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3
    Storage Conditions:
    Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
    Gene Symbol:
    • NAT1
    • NET
    • NET1
    • SLC6A5
    Quality Assurance:
    Routinely evaluated by western blot.
    Antibody Category:
    Neuroscience
    Antibody Sub-Category:
    Neurotransmitters & Receptors
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Format:
    Purified
    Host:
    Rabbit
    Concentration:
    1 mg/mL
    Antibody Type:
    Polyclonal Antibody
    Purification Method:
    Immunoaffinity purified

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    Synthetic Linear Peptide 详细描述见链接：http://www.millipore.com/catalogue/item/AB2234

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    图标文献和实验
    相关实验

    • Transporter Current Measurements

      Na+ /K+ pump, Na+ /Ca2+ exchanger, glutamate transporter and other transporters for dopamine, norepinephrine, GABA, and others, are all electrogenic. These transporters or exchanger transport Na+ ions, with or without transmitters

    • Anti-P-CREB

      policeman.4. Put the extract into an eppendorf and boil for 5 min., cool on ice.5. Load onto 10% SDS-PAGE. I usually load about 1/5 of the lysate from a 60 mm dish. This is about 100 μg protein for PC12 cells.6. After electrophoresis, electrotransfer

    • Production and Characterization of Anti-Cocaine Catalytic Antibodies

      is the dopamine reuptake transporter at the nucleus accumbens. By blocking reuptake, cocaine enhances dopaminergic neurotransmission, which activates the reward pathway. The result is reinforcement of drug-taking behavior in species ranging from mouse to man

    查看更多相关实验 >
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