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Anti-Integrin beta1, phospho-s

pecific [Thr788/Thr789]; 100 μL
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  • 询价
  • AB1929
  • 2025年07月15日
  • Western Blotting
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围

      Western Blotting

    • 宿主

      Rabbit

    • 库存

      大量

    • 适应物种

      Human

    • 抗原来源

      0

    • 是否单克隆

      2

    • 规格

      100 μL

    Species Reactivity Key Applications Host Format Antibody Type
    H WB Rabbit Affinity Purified Polyclonal Antibody
    Description:
    Anti-Integrin β1, phospho-specific [Thr788/Thr789]
    Background Information:
    Integrin beta1 is a transmembrane glycoprotein that forms noncovalent complexes with various alpha integrin subunits to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. Interactions between integrins and extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. Phosphorylation of threonines 788 and 789 on integrin beta1 receptor may play a key role in cell-cycle dependent regulation.
    Alternate Names:
    CD29; Integrin VLA-4 subunit beta; Fibronectin receptor subunit beta
    Specificity:
    The antibody detects a 130 kDa protein of integrin beta1 receptor.
    Key Applications:
    Western Blotting
    Application Notes:
    Western Blot: 1:1000.

    Optimal working dilutions must be determined by end user.
    Species Reactivity:
    Human
    Immunogen:
    Phosphorylated synthetic peptide corresponding to amino acid residues surrounding and including threonine 788/789 of the human beta1 integrin. The immunogen sequence is 100% identical in mouse, rat and chicken integrin beta1.
    Epitope:
    pT788/789
    Modifications:
    Phosphorylation
    Presentation:
    Antibody is cross-adsorbed to nonphospho-peptide corresponding to the site of phosphorylation then affinity purified using phosphorylated integrin beta1 receptor (Thr788/789) peptide. Antibody is supplied in Dulbecco's phosphate-buffered saline (without Mg2+ or Ca2+ ), pH 7.3, 50% glycerol and 1 mg/mL BSA.
    Storage Conditions:
    Maintain at -20°C for up to one year from date of receipt. Avoid repeated freeze/thaw cycles.
    Gene Symbol:
    • ITGB1
    • GPIIA
    • OTTHUMP00000063731
    • OTTHUMP00000046253
    • OTTHUMP00000063733
    • VLAB
    • OTTHUMP00000063732
    • MDF2
    • FNRB
    • CD29
    • MSK12
    Antibody Category:
    Cell Structure
    Antibody Sub-Category:
    Integrins
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Chemicon (Millipore)
    Format:
    Affinity Purified
    Host:
    Rabbit
    Antibody Type:
    Polyclonal Antibody

    更多产品技术资讯,请访问密理博中国博客:http://blog.milliporechina.com

    Phosphorylated synthetic peptide corresponding to amino acid residues surrounding and including threonine 788/789 of the human beta1 integrin. The immunogen sequence is 100% identical in mouse, rat and chicken integrin beta1. 详细描述见链接:http://www.millipore.com/catalogue/item/AB1929

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    图标文献和实验
    相关实验
    • Using Phospho‐Motif Antibodies to Determine Kinase Substrates

      Figure 18.20.1 The specificity of phospho‐motif antibodies. HeLa cells were serum‐starved for 24 hr prior to being stimulated with 50 ng/ml IGF‐1 or 100 nM PMA for 10 min. Lysates were immunoblotted with anti‐Akt/PKB phospho‐motif (left panel

    • Cell Staining for Senescence-Associated beta-Galactosidase (SA-beta-Gal) Activity

      as before in PBS two times. 7. Add between 1 to 2 ml of Staining Solution per 35 mm culture dish or cover slide. 8. Incubate for at least 2 hr at 37°C (do not incubate in a CO2 incubator; see Hint #3). Recipes Staining Solution 1 ml of 100 mM K3Fe(CN

    • Beta-gal Assay

      phosphate buffer, pH 7, you first need to make two solutions: Solution A: 27.2 g KH2PO4 in 1 L water. Solution B: 34.8 g K2HPO4 in 1 L water. Mix 39 ml Solution A and 61 ml Solution B and then add 100 ml of water.

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    Anti-Integrin beta1, phospho-specific [Thr788/Thr789]; 100 μL
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