- 询价
- AB2231
- 2025年06月28日
- Western Blotting
- Rabbit
- Rabbit
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- 详细信息
- 技术资料
- 应用范围：
Western Blotting
- 宿主：
Rabbit
- 抗原来源：
0
- 库存：
大量
- 适应物种：
Rabbit
- 是否单克隆：
2
- 规格：
100 μg
Product Images
Western Blot Analysis:
Rat brain lysate was resolved by electrophoresis, transferred to PVDF and probed with anti-DAT (0.5 ug/ml). Proteins were ...
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| Rb | WB | Rabbit | Purified | Polyclonal Antibody |
Description:
Anti-Dopamine Transporter; 100 µg
Background Information:
Plasmalemmal neurotransmitter transporters sequester synaptic and peri synaptic transmitter into presynaptic elements. The Dopamine Transporter (DAT), a 12 transmembrane domain transporter with the N and C terminal regions located within the cytoplasm is responsible for the reaccumulation of dopamine after it has been released. Levels of DAT protein expression are altered by chronic drug administration. The activity of the DAT reuptake carrier is sodium dependent, and it is suspected to play a role in such neurologic and psychiatric disorders as Parkinson's disease, Tourette's disease, schizophrenia, and addiction. DAT is also the target of several “DAT-blockers” including amphetamines and cocaine. These chemicals inhibit the action of DAT and, to a lesser extent, the other monoamine transporters, but their effects are mediated by separate mechanisms.
Alternate Names:
- DA transporter
- dopamine transporter
- solute carrier family 6 (neurotransmitter transporter, dopamine),member 3
- variable number tandem repeat (VNTR)
Specificity:
Cat. AB2231 recognizes the N-terminus of the reduced and non reduced forms of DAT.
Key Applications:
Western Blotting
Species Reactivity:
Rabbit
Species Reactivity Note:
Rat and Mouse. Reactivity with other species has not been determined.
Immunogen:
Synthetic Linear Peptide
Epitope:
N-terminus
Molecular Weight:
~ 50 – 80 kDa
Reduced form at approx 50 kDa and Non-reduced form at approx. 80 kDa
Reduced form at approx 50 kDa and Non-reduced form at approx. 80 kDa
Control:
Rat Brain Lysate.
Presentation:
Purified Antibody in PBS with 0.1% NaN3
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.
Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.
Gene Symbol:
- DAT
- DAT 1
Quality Assurance:
Routinelyevaluated by western blot on rat brain lysate.
Antibody Category:
Neuroscience
Antibody Sub-Category:
Ion Channels & Transporters
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Format:
Purified
Host:
Rabbit
Concentration:
1 mg/mL
Antibody Type:
Polyclonal Antibody
更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com
Synthetic Linear Peptide 详细描述见链接：http://www.millipore.com/catalogue/item/AB2231
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Anti-Dopamine Transporter; 100 μg
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