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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Phenoxodiol
- 库存:
10
- 供应商:
TargetMol
- CAS号:
81267-65-4
- 规格:
25 mg/1 mL/1 mg/5 mg/2 mg/10 mg
| 规格: | 25 mg | 产品价格: | ¥4470.0 |
|---|---|---|---|
| 规格: | 1 mL | 产品价格: | ¥1790.0 |
| 规格: | 1 mg | 产品价格: | ¥678.0 |
| 规格: | 5 mg | 产品价格: | ¥1630.0 |
| 规格: | 2 mg | 产品价格: | ¥992.0 |
| 规格: | 10 mg | 产品价格: | ¥2650.0 |
Product Introduction
Bioactivity
英文名:Phenoxodiol
描述:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Phenoxodiol also inhibits DNA topoisomerase II.

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文献和实验Modulation of Apoptosis to Reverse Chemoresistance
the role of apoptosis in ovarian cancer and the use of phenoxodiol as a model for the regulation of apoptosis and potential use as chemosensitizer for chemoresistant ovarian cancer cells.
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