Fucosylated Ganglioside GM1 (p

一种含岩藻糖的糖鞘脂，已在分离的小细胞肺癌肿瘤中发现；在体外和体内小细胞肺癌裸鼠异种移植模型中从小细胞肺癌细胞中脱落；可在小细胞肺癌患者的血浆中检测到；在大鼠C6胶质瘤培养细胞中表达时与表达神经节苷脂GM1的细胞结合水平相似，可与霍乱毒素结合。A fucose-containing glycosphingolipid; has been found in isolated SCLC tumors; shed from SCLC cells in vitro and in vivo in SCLC nude mouse xenograft models; can be detected in human plasma from SCLC patients; binds to cholera toxin when expressed in rat C6 glioma cultured cells to similar levels as cells expressing ganglioside GM1.