H-Gly-Pro-Arg-Pro-OH (acetate)

Modulation of G Proteins in Rat Striatum by Neuroleptic Drugs and a Peptidomimetic Analog of Pro-Leu-Gly-NH2

Although the dopamine hypothesis of schizophrenia has gained wide acceptance, it has recently become clear that it requires revision (Seeman and Niznik, 1990 ; Ellison, 1994 ; Kahn and Davis, 1995 ). The original hypothesis asserts

Silver Acetate Autometallography (AMG)

hybridization, in situ PCR and in situ 3SR techniques were born. Silver Acetate AMG was developed and optimized during research visits of Gerhard W. HACKER at the University of Uppsala, Sweden, in joint collaboration with Gorm DANSCHER (Aarhus, DK) and Lars

环肽的合成方法

为缩合剂，保持pH 8.5～9，反应4天，得到相应的环六肽和环五肽，收率在15%～50%之间。生物活性实验表明所有的环六肽对细胞粘附的抑制作用均明显低于线性肽GRGDS。环五肽中也只有Cyclo（RGDdFV）和Cyclo（RGDFd-V）对Laminin P1的细胞粘附具有明显的抑制作用。 对于某些在碱性条件下易分解的目的物，反应过程当中应用惰性气体进行保护，例如，线性多肽H-Asp（Fmoc）- d-Ser-Phe- D-Phe- Arg- Gly - OH在无水DMF中，加入5倍量NaHCO