- ￥960
- Solarbio
- K008524P
- 北京
- 2025年11月27日
- IHC
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
DNMT3L
- 应用范围：
IHC
- 宿主：
Rabbit
- 适应物种：
Human
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 形态：
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
- 亚型：
IgG
- 免疫原：
Recombinant protein of human DNMT3L
| 单位 | 支 |
| 英文名称 | Anti-DNMT3L Polyclonal Antibody |
| 别名 | DNMT3L |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:10-50. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UJW3 |
| 蛋白分子量 | 44 kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human DNMT3L |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul 100ul |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Immunohistochemistry of paraffin-embedded Human colorectal cancer with DNMT3L antibody diluted at 1:10
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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