Anti-NOD1 Polyclonal Antibody

产品简介

英文名称	Anti-NOD1 Polyclonal Antibody
宿主	Rabbit
别名	CARD4； CLR7.1； NLRC1
稀释比例	IHC 1:50-200.
蛋白分子量	28/108kDa
Gene ID	10392
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human NOD1
亚细胞定位	Cytoplasm
Swiss Prot	Q9Y239
背景资料	This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
Public Immunogen Range	604-953aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human colorectal cancer with NOD1 antibody diluted at 1:100

Immunohistochemistry of paraffin-embedded Human lung cancer with NOD1 antibody diluted at 1:100

Immunohistochemistry of paraffin-embedded Human pancreatic cancer with NOD1 antibody diluted at 1:100