Anti-COPS2 Polyclonal Antibody

产品简介

英文名称	Anti-COPS2 Polyclonal Antibody
宿主	Rabbit
别名	COPS2;ALIEN;CSN2;SGN2;TRIP15;COP9 signalosome subunit 2
稀释比例	WB 1:1000-3000.
蛋白分子量	52kDa
Gene ID	9318
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human COPS2
亚细胞定位	Nucleus Cytoplasm
Swiss Prot	P61201
背景资料	Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Public Immunogen Range	1-440aa
克隆类型	Polyclonal Antibody
交叉反应	Human Monkey Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图