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茶黄素|4670-05-7|Theaflavin

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  • 仕诺达
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  • 2025年11月14日
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    • 英文名

      Theaflavin

    • 库存

      999

    • 供应商

      仕诺达生物

    • CAS号

      4670-05-7

    • 规格

      10mg,分析标准品,HPLC≥98%(多种规格可选)/20mg,分析标准品,HPLC≥98%

    规格:10mg,分析标准品,HPLC≥98%(多种规格可选)产品价格:¥800.0
    规格:20mg,分析标准品,HPLC≥98%产品价格:¥1400.0

    产品细节图片1 

    简介

    茶黄素是一种常见的植物化合物,也称为儿茶素。它存在于茶叶、葡萄酒和巧克力等食物中。

    茶黄素具有许多重要的性质和健康效益。茶黄素还具有抗炎、抗菌和抗癌的特性,可以改善心脏健康,降低胆固醇和血糖水平,增强免疫系统。

    茶黄素的制取方法主要是从茶叶中提取。将茶叶进行粉碎,并使用合适的溶剂(如水或有机溶剂)进行提取。然后,通过蒸馏、浓缩和纯化等步骤,分离和纯化得到茶黄素。

    茶黄素的安全性,一般认为它是相对安全的,但仍需在适量的摄入范围内使用。高剂量的茶黄素摄入可能导致一些不良反应,如消化不良、头痛、失眠等。对于孕妇、哺乳期妇女和某些特定的疾病患者,
    应在医生的指导下使用茶黄素补充剂。对于个别人群可能存在过敏反应,如皮肤瘙痒、呼吸困难等,应立即停止使用并就医。
    中文名茶黄素
    英文名5H-Benzocyclohepten-5-one, 1,8-bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-
    别名茶黄素
    茶黄素(TF)
    茶黄素(标准品)
    茶黄素(TF1)
    茶黄素, 来源于绿茶
    3,4,6-三羟基-1,8-双(3Α,5,7-三羟基-2Α-苯并二氢吡喃基)-5H-苯并环烯-5-酮
    3,4,5-三羟基-1,8-双[(2R,3R)-3,5,7-三羟基-2-苯并二氢吡喃基]-6-苯并[7]环烯酮
    3,4,6-三羟基-1,8-双((2R,3R)-3,5,7-三羟基苯并二氢吡喃-2-基)-5H-苯并[7]环烯-5-酮
    英文别名THEAFLAVIN
    Theaflavin
    Theaflavins
    Theaflavine
    THEAFLAVINE
    Theaflavin 1
    6-trihydroxy-
    (-)-Theaflavin
    1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-5h-benzocyclohepten-5-one
    5h-benzocyclohepten-5-one,1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-3,
    5H-Benzocyclohepten-5-one,3,4,6-trihydroxy-1,8-bis(3a,5,7-trihydroxy-2a-chromanyl)-
    3,4,6-Trihydroxy-1,8-bis(3,4-dihydro-3α,5,7-trihydroxy-2H-1-benzopyran-2α-yl)-5H-benzocycloheptene-5-one
    6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one
    5H-Benzocyclohepten-5-one, 1,8-bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-
    5H-Benzocyclohepten-5-one,1,8-bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-,[2R-[2a(2R*,3R*),3a]]-
    CAS4670-05-7
    化学式C29H24O12
    分子量564.49
    密度1.777±0.06 g/cm3(Predicted)
    熔点237-240 °C (decomp)(Solv: water (7732-18-5))
    沸点1079.6±65.0 °C(Predicted)
    闪点336.5°C
    溶解度DMSO (微溶) 、甲醇 (微溶)
    酸度系数6.65±0.20(Predicted)
    存储条件-20°C
    外观整洁
    颜色Red to Very Dark Red
    物化性质来源于茶叶发酵的产物
    MDL号MFCD03427500
     

    核磁图谱:

     

    产品细节图片2

    计算化学数据:

    • 分子量:564.49366g/mol
    •  
    • 化合物是否规范:True
    •  
    • 疏水参数计算参考值(XLogP3-AA):2.4
    •  
    • 准确质量:564.12677620
    •  
    • 同位素质量:564.12677620
    •  
    • 复杂度:1060
    •  
    • 可旋转化学键数量:2
    •  
    • 氢键供体数量:9
    •  
    • 氢键受体计数:12
    •  
    • 拓扑极表面积:218
    •  
    • 重原子数量:41
    •  
    • 确定原子立构中心数量:4
    •  
    • 不确定原子立构中心数量:0
    •  
    • 确定化学键立构中心数量:0
    •  
    • 不确定化学键立构中心数量:0
    •  
    • 同位素原子计数:0
    •  
    • 共价键单元数量:1
    •  
    • CACTVS Substructure Key Fingerprint:AAADceB4PAAAAAAAAAAAAAAAAAAAAAAAAAA0aMECBAAAAACRUAAAGgAACAAADBSgmAIwBoAABgCIAqBSAAICCAAkIAAAiAFGiMgNNzaGNRqCeWGl4BULuYfK7PzOoAADCAAYQABAAAYQADCAAAAAAAAAAA==

     产品细节图片3

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    图标文献和实验
    该产品被引用文献

    1. 吴满霞 钟国花 何四海 等. "皖海红美人"红茶生产加工技术初探[J]. 茶业通报 2020(2):81-84.
    2. 潘顺顺 赖幸菲 孙伶俐 黎秋华 向丽敏 孙世利.不同季节翠玉品种3大茶类生化成分及抗氧化活性研究[J].食品研究与开发 2017 38(09):22-27.
    3. 黎秋华 赖幸菲 向丽敏 等. 不同树龄英红九号红茶的生化成分差异分析[J]. 食品研究与开发 2018.
    4. 代淑华, 江清林, 辛华,等. 茶黄素和脑血通口服液治疗大鼠动脉粥样硬化的实验研究[J]. 安徽医科大学学报, 2013(10):1198-1201.
    5. 赖幸菲, 孙世利, 李裕南,等. 金萱品种夏暑茶类的生化成分分析及其抗氧化活性研究[J]. 食品工业科技, 2015, 36(021):73-77.
    6. Fang, Shimao, et al. "Geographical origin traceability of Keemun black tea based on its non‐volatile composition combined with chemometrics." Journal of the Science of Food and Agriculture 99.15 (2019): 6937-6943.
    7. Tai, Lingling, et al. "Anti-hyperuricemic effects of three theaflavins isolated from black tea in hyperuricemic mice." Journal of Functional Foods 66 (2020): 103803
    8. Hua, Jinjie, et al. "Influence of enzyme source and catechins on theaflavins formation during in vitro liquid-state fermentation." LWT 139 (2021): 110291
    9. Qu, Fengfeng, et al. "Comparison of the Effects of Green and Black Tea Extracts on Na+/K+‐ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice." Molecular nutrition & food research 63.17 (2019): 1801039
    10. [IF=7.514] Xuemei Guo et al."An emerging strategy for evaluating the grades of Keemun black tea by combinatory liquid chromatography-Orbitrap mass spectrometry-based untargeted metabolomics and inhibition effects on α-glucosidase and α-amylase."Food Chem. 2018 Apr;2
    11. [IF=4.952] Fengfeng Qu et al."Effect of different drying methods on the sensory quality and chemical components of black tea."Lwt Food Sci Technol. 2019 Jan;99:112
    12. [IF=2.769] Guobin Xia et al."Tannase-mediated biotransformation assisted separation and purification of theaflavin and epigallocatechin by high speed counter current chromatography and preparative high performance liquid chromatography: A comparative study."Microsc
    13. [IF=7.514] Mingchun Wen et al."Identification of 4-O-p-coumaroylquinic acid as astringent compound of Keemun black tea by efficient integrated approaches of mass spectrometry, turbidity analysis and sensory evaluation."Food Chem. 2022 Jan;368:130803
    14. [IF=7.514] Ai Huang et al."Targeted and nontargeted metabolomics analysis for determining the effect of storage time on the metabolites and taste quality of keemun black tea."Food Chem. 2021 Oct;359:129950
    15. [IF=6.475] Mingchun Wen et al."Quantitative changes in monosaccharides of Keemun black tea and qualitative analysis of theaflavins-glucose adducts during processing."Food Res Int. 2021 Oct;148:110588
    16. [IF=6.419] Fengfeng Qu et al."Study on mechanism of low bioavailability of black tea theaflavins by using Caco-2 cell monolayer."Drug Deliv. 2021;28(1):1737-1747
    17. [IF=4.952] Jinjie Hua et al."Influence of enzyme source and catechins on theaflavins formation during in vitro liquid-state fermentation."Lwt Food Sci Technol. 2021 Mar;139:110291
    18. [IF=4.952] Fengfeng Qu et al."The new insight into the influence of fermentation temperature on quality and bioactivities of black tea."Lwt Food Sci Technol. 2020 Jan;117:108646
    19. [IF=4.653] Fengfeng Qu et al."Comparison of the Effects of Green and Black Tea Extracts on Na+/K+‐ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice."Mol Nutr Food Res. 2019 Sep;63(17):1801039
    20. [IF=4.556] Jinjie Hua et al."Effects of novel fermentation method on the biochemical components change and quality formation of Congou black tea."J Food Compos Anal. 2021 Mar;96:103751
    21. [IF=4.35] Bernard Ntezimana et al."Different Withering Times Affect Sensory Qualities, Chemical Components, and Nutritional Characteristics of Black Tea."Foods. 2021 Nov;10(11):2627
    22. [IF=4.192] Wenji Zhang et al."Theaflavin TF3 Relieves Hepatocyte Lipid Deposition through Activating an AMPK Signaling Pathway by targeting Plasma Kallikrein."J Agr Food Chem. 2020;68(9):2673–2683
    23. [IF=4.171] Xin-Xian Xu et al."Theaflavin protects chondrocytes against apoptosis and senescence via regulating Nrf2 and ameliorates murine osteoarthritis.."Food Funct. 2021 Mar;12(4):1590-1602
    24. [IF=3.701] Lingling Tai et al."Anti-hyperuricemic effects of three theaflavins isolated from black tea in hyperuricemic mice."J Funct Foods. 2020 Mar;66:103803
    25. [IF=3.638] Shimao Fang et al."Geographical origin traceability of Keemun black tea based on its non-volatile composition combined with chemometrics."J Sci Food Agr. 2019 Dec;99(15):6937-6943
    26. [IF=2.19] Xiaofen Wu et al."Effect of fermentation time and temperature on the of polyphenol compounds change of different Congou black tea."J Food Process Pres. 2021 Oct;45(10):e15844
    27. [IF=7.514] Yuqing Cui et al."Identification of low-molecular-weight color contributors of black tea infusion by metabolomics analysis based on UV–visible spectroscopy and mass spectrometry."Food Chem. 2022 Aug;386:132788
    28. [IF=6.475] Guoping Lai et al."Free, soluble conjugated and insoluble bonded phenolic acids in Keemun black tea: From UPLC-QQQ-MS/MS method development to chemical shifts monitoring during processing."Food Res Int. 2022 May;155:111041
    29. [IF=4.952] Huajie Wang et al."Novel insight into the effect of fermentation time on quality of Yunnan Congou black tea."Lwt Food Sci Technol. 2022 Feb;155:112939
    30. [IF=5.396] Chunyin Qin et al."Comparison on the chemical composition, antioxidant, anti-inflammatory, α-amylase and α-glycosidase inhibitory activities of the supernatant and cream from black tea infusion."Food & Function. 2022 Apr;:

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    ¥800 - 1400