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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin E1
- 亚型:
Phospho-Cyclin E1
- 形态:
Phospho-Cyclin E1
- 保存条件:
-20°C
- 克隆性:
单克隆
- 标记物:
Phospho-Cyclin E1
- 适应物种:
WB, IH, IF/IC
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin E1
- 目录编号:
Phospho-Cyclin E1
- 级别:
Phospho-Cyclin E1
- 库存:
Phospho-Cyclin E1
- 供应商:
艾美捷
- 宿主:
Rabbit
- 应用范围:
WB, IH, IF/IC
- 浓度:
Phospho-Cyclin E1
- 靶点:
Phospho-Cyclin E1
- 抗体英文名:
Phospho-Cyclin E1
- 抗体名:
磷酸环素E1
- 规格:
100ul
产品名称:磷酸环素E1/磷酸环素E1/磷酸环素E1-Phospho-Cyclin E1 /Phospho-Cyclin E1 /Phospho-Cyclin E1
产品货号:A1154-100-E 产品规格:100ul 应用类型:WB, IH, IF/IC
保存建议:磷酸环素E1/磷酸环素E1/磷酸环素E1-Phospho-Cyclin E1 /Phospho-Cyclin E1 /Phospho-Cyclin E1 -20°C
背景资料:Cyclin E1 is a regulatory subunit of the CDK2 kinase. It is central for the regulation of the G1/S transition and its abundance is tightly regulated throughout the cell cycle via ubiquitination. Cyclin E has been the subject of intense study in relation to tumorigenesis and cancer management and prognosis. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
点击:磷酸环素E1/磷酸环素E1/磷酸环素E1-Phospho-Cyclin E1 /Phospho-Cyclin E1 /Phospho-Cyclin E1 查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.
艾美捷科技有限公司,通过提供完整的产品和服务体系、便利的客户关系和供应链管理,为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力,提供有竞争力的生物医学产品和服务,持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系,目前已成为众多国际知名品牌的中国总代理或一级代理,主要包括:AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等,可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级,全方位实验服务项目上线啦~
关键词:Phospho-Cyclin E1 /Phospho-Cyclin E1 /Phospho-Cyclin E1 ,磷酸环素E1/磷酸环素E1/磷酸环素E1,CCNE1
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文献和实验Purification of E1 and E1-Like Enzymes
physical and mechanistic features of the E1 family appear well conserved. Formation of an obligatory E1-ubiquitin thiol ester intermediate forms the basis of a one-step covalent purification of the enzyme on ubiquitin-linked affinity columns
Immunoprecipitation of E1 A-Containing Protein Complexes
of monoclonal antibodies and the fortuitous properties of nonionic detergents. These highly efficient and specific means of isolating protein complexes from cell lysates, while detailed here for E1Acontaining protein complexes, have general application
Ovarian carcinoma is the most lethal tumor of the female genital tract and continues to be a major cause of female cancer deaths, largely as a function of early abdominal seeding producing carcinomatosis. The high rate of mortality is mainly
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