
Notch 1 Antibody,Notch-1,Notch
1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1- 询价
- Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
- 兔
- Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to residues surrounding amino acid 1760 of mouse Notch1
- 亚型:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 形态:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 保存条件:
提供的Notch 1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Notch 1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
- 克隆性:
单克隆
- 标记物:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 适应物种:
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
Synthetic peptide corresponding to residues surrounding amino acid 1760 of mouse Notch1
- 目录编号:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 级别:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 库存:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 供应商:
艾美捷
- 宿主:
兔
- 应用范围:
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
- 浓度:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 靶点:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 抗体英文名:
Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
- 抗体名:
Notch 1抗体
- 规格:
100ug
产品名称:Notch 1抗体/Notch 1抗体/Notch 1抗体-Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1
产品货号:3881-100-E 产品规格:100ug 应用类型:Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
保存建议:Notch 1抗体/Notch 1抗体/Notch 1抗体-Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1提供的Notch 1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Notch 1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
背景资料:Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.
点击:Notch 1抗体/Notch 1抗体/Notch 1抗体-Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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关键词:Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1/Notch 1 Antibody,Notch-1,Notch 1,NOTCH1,TAN1,hN1,Notch 1抗体/Notch 1抗体/Notch 1抗体,MSH6
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文献和实验protein c-myc and jagged1. Simultaneously, the Wnt and Notch signaling pathways were co-activated, as confirmed by the increased expression of β-catenin and notch1. Plasmids expressing Lef1 and ΔNLef1, a construct in which the β-catenin-binding domain
,它与 Wnt 结合后被激活,并抑制下游蛋白质复合物,包括 axin、GSK- 3、与 APC 蛋白。axin/GSK- 3 /APC 复合体可促进细胞内信号分子 β-catenin 的降解。当「β-catenin 降解复合物」被抑制后,胞浆内的 β-catenin 得以稳定存在,部分 β-catenin 进入细胞核与 TCF/LEF 转录因子家族作用并促进特定基因的表达。7. Notch signaling pathwayNotch 通路调控机制:Notch 蛋白横穿过细胞膜,部分在细胞内而部分在细胞
ChIP数据分析:ChIP结果图来PK,谁才是发文的香饽饽?
上下游的reads覆盖深度,红色表示覆盖深度高、目的蛋白结合多。我们在不少文献中都可以看到这张图,既可以完整展示,也可以部分展示。 两组样本(蓝色和橙色)组蛋白修饰H3K27ac分布,同一基因(位点)在一组中修饰程度较高,而在另一组中修饰程度较低。(图片来源:TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer)
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