Notch 1 (NOTCH1) 抗体

Notch 1 (NOTCH1) 抗体
抗原
Notch 1 (NOTCH1)
别名 notch1, NOTCH1, hn1, tan1, notch, xotch, xnotch, notch-1, xnotch1, TAN1, hN1, 9930111A19Rik, Mis6, N1, Tan1, lin-12, NOTCH, Xotch, notch1-a
适用
其他选择 人, 小鼠
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (MN1A)
标记
其他选择 PE
Notch 1 (NOTCH1) 抗体应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 5个引用可参考
规格 100 tests
发货至 中国 (更改)
产品细节
免疫原 Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
克隆位点 MN1A
亚型 IgG1
特异性 This antibody is specific for Notch1.
纯化方法 Affinity Chromatography on Protein G
目标详细情况
别名 NOTCH1
背景 Notch1 is a single transmembrane receptor which is expressed in a range of cells including hematopoietic cells in mouse fetal liver, adult thymus and bone marrow. Notch1 plays a role in embryonic development and tissue homeostasis in the adult. Recent work has suggested a further role for this receptor in the regulation of lymphopoieisis and myelopoiesis. Following ligand binding, Notch1 is cleaved in the transmembrane domain, releasing the Notch intracellular domain (NICD) to translocate to the nucleus, where it plays a role in the modulation of gene expression.Synonyms: Neurogenic locus notch homolog protein 1, Notch 1, TAN1, hN1
基因ID 4851
Notch 1 (NOTCH1) 抗体UniProt P46531
研究领域 Receptors, Signaling, Inflammation, Immunology
使用细节
应用备注 Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 1x10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理
溶解方式 Restore with 1 mL distilled water.
浓度 0.1 mg/mL
缓冲液 PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Original vial: 1 year at 2-8 °C. After reconstitution, aliquot and freeze stock solution at -20 °C.
有效期 12 months
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