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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana BiP proteins: BiP1 UniProt:Q9LKR3, TAIR: At5g28540, BiP2 UniProt: F4K007, TAIR: At5g42020, BiP3 UniProt:Q8H1B3 ,TAIR:At1g09080
- 形态:
Immunogen affinity purified total IgY. in PBS pH 7.4.
- 保存条件:
Store at 4°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- 克隆性:
Polyclonal
- 适应物种:
Arabidopsis thaliana, Hordeum vulgare, Physcomitrium patens, Spinacia oleracea, Zea mays
- 供应商:
Agrisera
- 宿主:
Chicken
- 应用范围:
Immunofluorescence (IF), Western blot (WB)
- 靶点:
Anti-BiP | Lumenal-binding protein (chicken antibody)
- 抗体英文名:
Anti-BiP | Lumenal-binding protein (chicken antibody)
- 抗体名:
Anti-BiP | Lumenal-binding protein (chicken antibody)
- 规格:
100 µg
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文献和实验ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
+/- ++ Goat - ++ Chicken - + Table II Species Protein
重链结合蛋白(heavy-chain binding protein, Bip)
Bip是重链结合蛋白的简称,因为它能够同IgG抗体的重链结合而得名。Bip是一类分子伴侣,属于Hsp70家族,在内质网中有两个作用。 第一,Bip同进入内质网的未折叠蛋白质的疏水氨基酸结合,防止多肽链不正确地折叠和聚合。然后Bip同ATP结合并通过ATP的水解释放出结合的多肽。在多数情况下,释放出的多肽很快折叠,或者同别的亚基共同组装成完整的蛋白质。正确折叠和装配的蛋白质不会同Bip再结合,但是,如果蛋白质进行了不正确的折叠或错误的装配,Bip会马上同这种
on safety and efficacy. Therefore, assessment of immunogenicity of the therapeutic protein is an essential part of its clinical development. This involves testing strategies which provide relevant information on antibody responses. This chapter describes
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