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Cbz-N-amido-PEG20-acid
MCE 国际站：Cbz-N-amido-PEG20-acid
产品活性：Cbz-N-amido-PEG20-acid 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
研究领域：PROTAC
作用靶点：PROTAC Linkers
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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文献和实验A Method for Assaying Deubiquitinating Enzymes
using 125 I-labeled Ub-PESTc. We also compare the sensitivity of this method to that using a fluorogenic peptide substrate, carbobenzoxy-LRGG-7-amido-4-methylcoumarin (Cbz-LRGG-AMC), that has also been used as a substrate for DUBs (19 ). 20
Preparation of Carboxypeptidase Y and Its Properties
. ⑶ Activation: The precipitate is dissolved in 300ml of 0.05 M sodium acetate buffer, pH 5.0, and adjusted to pH 5.0 with 1 M acetic acid under stirring, then incubated at 25℃ for an additional 18～20h with a few drops of toluene added. ⑷
CarbonCarbon Bond-Forming Enzymes for the Synthesis of Non-natural Amino Acids
An enzymatic methodology for the preparation of β-hydroxy-α-amino acid derivatives is described. The method consists of the stereoselective aldol addition reaction of glycine to N -Cbz-amino aldehydes furnishing 3-hydroxy-2,4-diaminobutyric
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